Pittsburgh Defenders Schedule
All times Eastern
Complete Schedule
| March 23, 2019 | L | Pittsburgh Defenders 18 at West Virginia Roughriders 95 | Final |
| March 30, 2019 | L | New England Bobcats 68 at Pittsburgh Defenders 30 | Final |
| April 5, 2019 | Jersey Flight at Pittsburgh Defenders | Ppd. | |
| April 13, 2019 | New England Bobcats at Pittsburgh Defenders | Cancelled | |
| April 20, 2019 | Indianapolis Enforcers at Pittsburgh Defenders | Cancelled | |
| May 4, 2019 | L | West Virginia Roughriders 74 at Pittsburgh Defenders 0 | Final |
| May 11, 2019 | L | Pittsburgh Defenders 12 at Jersey Flight 56 | Final |
| May 25, 2019 | Pittsburgh Defenders at Indianapolis Enforcers | Cancelled | |
| June 1, 2019 | Pittsburgh Defenders at New England Bobcats | Cancelled |
