| | | |
| March 15, 2025 | L | Billings Outlaws 78 at Oregon Lightning 36 | Final |
| March 22, 2025 | L | Oregon Lightning 28 at Washington Wolfpack 35 | Final |
| March 30, 2025 | W | Oregon Lightning 41 at Southwest Kansas Storm 40 | Final |
| April 4, 2025 | L | Oregon Lightning 32 at Nashville Kats 40 | Final |
| April 12, 2025 | | Oregon Lightning at Arizona Bandits | Cancelled |
| April 19, 2025 | L | Oregon Lightning 32 at Salina Liberty 47 | Final |
| April 25, 2025 | L | Washington Wolfpack 41 at Oregon Lightning 30 | Final |
| May 4, 2025 | W | Oregon Lightning 37 at Washington Wolfpack 9 | Final |
| May 12, 2025 | W | Corpus Christi Tritons 20 at Oregon Lightning 52 | Final |
| May 18, 2025 | W | Washington Wolfpack 20 at Oregon Lightning 52 | Final |
| May 24, 2025 | | Oregon Lightning at Arizona Bandits | Cancelled |
| May 24, 2025 | L | Oregon Lightning 36 at Nashville Kats 50 | Final |
| June 1, 2025 | L | Oregon Lightning 7 at Billings Outlaws 58 | Final |
| June 8, 2025 | W | Corpus Christi Tritons 24 at Oregon Lightning 40 | Final |
| June 14, 2025 | L | Billings Outlaws 40 at Oregon Lightning 38 | Final |
Oregon Lightning Schedule
