| | | |
| April 4, 2025 | L | Biloxi Shuckers 0 at Pensacola Blue Wahoos 4 | Final |
| April 5, 2025 | L | Biloxi Shuckers 1 at Pensacola Blue Wahoos 7 | Final |
| April 6, 2025 | L | Biloxi Shuckers 4 at Pensacola Blue Wahoos 8 | Final |
| April 8, 2025 | L | Columbus Clingstones 7 at Biloxi Shuckers 6 | Final (10) |
| April 9, 2025 | W | Columbus Clingstones 1 at Biloxi Shuckers 3 | Final |
| April 10, 2025 | L | Columbus Clingstones 5 at Biloxi Shuckers 2 | Final |
| April 11, 2025 | L | Columbus Clingstones 7 at Biloxi Shuckers 2 | Final |
| April 12, 2025 | L | Columbus Clingstones 8 at Biloxi Shuckers 3 | Final |
| April 13, 2025 | W | Columbus Clingstones 8 at Biloxi Shuckers 9 | Final |
| April 15, 2025 | W | Biloxi Shuckers 6 at Birmingham Barons 1 | Final |
| April 16, 2025 | W | Biloxi Shuckers 4 at Birmingham Barons 0 | Final |
| April 17, 2025 | L | Biloxi Shuckers 1 at Birmingham Barons 4 | Final |
| April 18, 2025 | W | Biloxi Shuckers 4 at Birmingham Barons 1 | Final |
| April 19, 2025 | L | Biloxi Shuckers 5 at Birmingham Barons 6 | Final |
| April 20, 2025 | W | Biloxi Shuckers 5 at Birmingham Barons 3 | Final (11) |
| April 22, 2025 | L | Montgomery Biscuits 2 at Biloxi Shuckers 0 | Final |
| April 23, 2025 | W | Montgomery Biscuits 1 at Biloxi Shuckers 10 | Final |
| April 24, 2025 | W | Montgomery Biscuits 3 at Biloxi Shuckers 7 | Final |
| April 25, 2025 | W | Montgomery Biscuits 6 at Biloxi Shuckers 8 | Final |
| April 26, 2025 | W | Montgomery Biscuits 1 at Biloxi Shuckers 6 | Final |
| April 27, 2025 | L | Montgomery Biscuits 6 at Biloxi Shuckers 3 | Final |
| April 29, 2025 | W | Biloxi Shuckers 9 at Columbus Clingstones 2 | Final |
| April 30, 2025 | W | Biloxi Shuckers 8 at Columbus Clingstones 5 | Final |
| May 1, 2025 | L | Biloxi Shuckers 5 at Columbus Clingstones 9 | Final |
| May 2, 2025 | W | Biloxi Shuckers 7 at Columbus Clingstones 4 | Final |
| May 3, 2025 | W | Biloxi Shuckers 8 at Columbus Clingstones 5 | Final |
| May 4, 2025 | W | Biloxi Shuckers 6 at Columbus Clingstones 1 | Final |
| May 6, 2025 | L | Pensacola Blue Wahoos 6 at Biloxi Shuckers 1 | Final |
| May 7, 2025 | | Pensacola Blue Wahoos at Biloxi Shuckers | Ppd. |
| May 8, 2025 | W | Pensacola Blue Wahoos 0 at Biloxi Shuckers 10 (Game 1) | Final (7) |
| May 8, 2025 | W | Pensacola Blue Wahoos 2 at Biloxi Shuckers 5 (Game 2) | Final (7) |
| May 9, 2025 | | Pensacola Blue Wahoos at Biloxi Shuckers | Ppd. |
| May 10, 2025 | W | Pensacola Blue Wahoos 1 at Biloxi Shuckers 4 (Game 1) | Final (7) |
| May 10, 2025 | W | Pensacola Blue Wahoos 4 at Biloxi Shuckers 7 (Game 2) | Final (7) |
| May 11, 2025 | W | Pensacola Blue Wahoos 1 at Biloxi Shuckers 5 | Final |
| May 13, 2025 | W | Biloxi Shuckers 10 at Montgomery Biscuits 4 | Final |
| May 14, 2025 | L | Biloxi Shuckers 4 at Montgomery Biscuits 7 | Final |
| May 15, 2025 | W | Biloxi Shuckers 9 at Montgomery Biscuits 3 | Final |
| May 16, 2025 | L | Biloxi Shuckers 3 at Montgomery Biscuits 4 | Final |
| May 17, 2025 | W | Biloxi Shuckers 6 at Montgomery Biscuits 3 | Final |
| May 18, 2025 | L | Biloxi Shuckers 1 at Montgomery Biscuits 4 | Final |
| May 20, 2025 | W | Knoxville Smokies 3 at Biloxi Shuckers 4 | Final |
| May 21, 2025 | L | Knoxville Smokies 8 at Biloxi Shuckers 6 | Final |
| May 22, 2025 | W | Knoxville Smokies 1 at Biloxi Shuckers 2 | Final |
| May 23, 2025 | W | Knoxville Smokies 1 at Biloxi Shuckers 3 | Final |
| May 24, 2025 | W | Knoxville Smokies 5 at Biloxi Shuckers 8 | Final |
| May 25, 2025 | W | Knoxville Smokies 6 at Biloxi Shuckers 7 | Final |
| May 27, 2025 | | Biloxi Shuckers at Rocket City Trash Pandas | Ppd. |
| May 28, 2025 | L | Biloxi Shuckers 2 at Rocket City Trash Pandas 3 | Final |
| May 29, 2025 | L | Biloxi Shuckers 1 at Rocket City Trash Pandas 2 (Game 1) | Final (7) |
| May 29, 2025 | L | Biloxi Shuckers 1 at Rocket City Trash Pandas 4 (Game 2) | Final (7) |
| May 30, 2025 | W | Biloxi Shuckers 2 at Rocket City Trash Pandas 1 | Final |
| May 31, 2025 | L | Biloxi Shuckers 1 at Rocket City Trash Pandas 2 | Final |
| June 1, 2025 | W | Biloxi Shuckers 5 at Rocket City Trash Pandas 1 | Final |
| June 3, 2025 | W | Montgomery Biscuits 0 at Biloxi Shuckers 2 | Final |
| June 4, 2025 | L | Montgomery Biscuits 5 at Biloxi Shuckers 3 | Final |
| June 5, 2025 | W | Montgomery Biscuits 5 at Biloxi Shuckers 13 | Final |
| June 6, 2025 | W | Montgomery Biscuits 2 at Biloxi Shuckers 5 | Final |
| June 7, 2025 | W | Montgomery Biscuits 5 at Biloxi Shuckers 8 | Final |
| June 8, 2025 | W | Montgomery Biscuits 4 at Biloxi Shuckers 6 | Final |
| June 10, 2025 | L | Biloxi Shuckers 9 at Chattanooga Lookouts 10 | Final |
| June 11, 2025 | L | Biloxi Shuckers 5 at Chattanooga Lookouts 6 | Final |
| June 12, 2025 | W | Biloxi Shuckers 6 at Chattanooga Lookouts 5 | Final (10) |
| June 13, 2025 | | Biloxi Shuckers at Chattanooga Lookouts | Ppd. |
| June 14, 2025 | W | Biloxi Shuckers 7 at Chattanooga Lookouts 2 (Game 1) | Final (7) |
| June 14, 2025 | L | Biloxi Shuckers 2 at Chattanooga Lookouts 5 (Game 2) | Final (7) |
| June 15, 2025 | W | Biloxi Shuckers 14 at Chattanooga Lookouts 8 | Final |
| June 17, 2025 | W | Knoxville Smokies 8 at Biloxi Shuckers 9 | Final |
| June 18, 2025 | W | Knoxville Smokies 2 at Biloxi Shuckers 6 | Final |
| June 19, 2025 | W | Knoxville Smokies 4 at Biloxi Shuckers 5 | Final |
| June 20, 2025 | L | Knoxville Smokies 10 at Biloxi Shuckers 6 | Final (10) |
| June 21, 2025 | L | Knoxville Smokies 4 at Biloxi Shuckers 3 | Final |
| June 22, 2025 | W | Knoxville Smokies 2 at Biloxi Shuckers 3 | Final |
| June 24, 2025 | L | Biloxi Shuckers 0 at Columbus Clingstones 2 | Final |
| June 25, 2025 | W | Biloxi Shuckers 5 at Columbus Clingstones 3 | Final (10) |
| June 26, 2025 | L | Biloxi Shuckers 1 at Columbus Clingstones 3 | Final |
| June 27, 2025 | W | Biloxi Shuckers 3 at Columbus Clingstones 0 | Final |
| June 28, 2025 | W | Biloxi Shuckers 6 at Columbus Clingstones 0 | Final |
| June 29, 2025 | W | Biloxi Shuckers 4 at Columbus Clingstones 1 | Final |
| July 1, 2025 | | Biloxi Shuckers at Pensacola Blue Wahoos | Susp. |
| July 2, 2025 | W | Biloxi Shuckers 10 at Pensacola Blue Wahoos 4 (Game 1) | Final |
| July 2, 2025 | L | Biloxi Shuckers 1 at Pensacola Blue Wahoos 5 (Game 2) | Final (7) |
| July 3, 2025 | L | Biloxi Shuckers 1 at Pensacola Blue Wahoos 2 | Final |
| July 4, 2025 | W | Pensacola Blue Wahoos 4 at Biloxi Shuckers 10 | Final |
| July 5, 2025 | W | Pensacola Blue Wahoos 4 at Biloxi Shuckers 6 | Final |
| July 6, 2025 | L | Pensacola Blue Wahoos 4 at Biloxi Shuckers 3 | Final |
| July 8, 2025 | L | Birmingham Barons 7 at Biloxi Shuckers 5 | Final |
| July 9, 2025 | L | Birmingham Barons 6 at Biloxi Shuckers 4 | Final |
| July 10, 2025 | L | Birmingham Barons 5 at Biloxi Shuckers 2 | Final |
| July 11, 2025 | L | Birmingham Barons 6 at Biloxi Shuckers 2 | Final |
| July 12, 2025 | L | Birmingham Barons 9 at Biloxi Shuckers 5 | Final |
| July 13, 2025 | L | Birmingham Barons 4 at Biloxi Shuckers 3 | Final (10) |
| July 18, 2025 | W | Biloxi Shuckers 4 at Montgomery Biscuits 2 | Final |
| July 19, 2025 | L | Biloxi Shuckers 0 at Montgomery Biscuits 1 | Final |
| July 20, 2025 | W | Biloxi Shuckers 6 at Montgomery Biscuits 5 | Final |
| July 22, 2025 | W | Rocket City Trash Pandas 2 at Biloxi Shuckers 5 | Final |
| July 23, 2025 | | Rocket City Trash Pandas at Biloxi Shuckers | Ppd. |
| July 24, 2025 | L | Rocket City Trash Pandas 5 at Biloxi Shuckers 1 (Game 1) | Final (7) |
| July 24, 2025 | W | Rocket City Trash Pandas 1 at Biloxi Shuckers 3 (Game 2) | Final (7) |
| July 25, 2025 | W | Rocket City Trash Pandas 2 at Biloxi Shuckers 3 | Final |
| July 26, 2025 | W | Rocket City Trash Pandas 2 at Biloxi Shuckers 7 | Final |
| July 27, 2025 | L | Rocket City Trash Pandas 3 at Biloxi Shuckers 2 | Final |
| July 29, 2025 | W | Biloxi Shuckers 7 at Pensacola Blue Wahoos 3 | Final |
| July 30, 2025 | L | Biloxi Shuckers 4 at Pensacola Blue Wahoos 8 | Final |
| July 31, 2025 | L | Biloxi Shuckers 3 at Pensacola Blue Wahoos 9 | Final |
| August 1, 2025 | L | Biloxi Shuckers 0 at Pensacola Blue Wahoos 1 | Final |
| August 2, 2025 | L | Biloxi Shuckers 2 at Pensacola Blue Wahoos 4 | Final |
| August 3, 2025 | L | Biloxi Shuckers 4 at Pensacola Blue Wahoos 8 | Final |
| August 5, 2025 | L | Biloxi Shuckers 4 at Knoxville Smokies 5 | Final |
| August 6, 2025 | W | Biloxi Shuckers 8 at Knoxville Smokies 4 | Final |
| August 7, 2025 | | Biloxi Shuckers at Knoxville Smokies | Susp. |
| August 8, 2025 | L | Biloxi Shuckers 0 at Knoxville Smokies 2 (Game 1) | Final |
| August 8, 2025 | W | Biloxi Shuckers 2 at Knoxville Smokies 1 (Game 2) | Final (7) |
| August 9, 2025 | W | Biloxi Shuckers 4 at Knoxville Smokies 2 | Final |
| August 10, 2025 | L | Biloxi Shuckers 2 at Knoxville Smokies 3 | Final |
| August 12, 2025 | W | Columbus Clingstones 6 at Biloxi Shuckers 7 | Final |
| August 13, 2025 | L | Columbus Clingstones 9 at Biloxi Shuckers 5 | Final |
| August 14, 2025 | W | Columbus Clingstones 8 at Biloxi Shuckers 14 | Final |
| August 15, 2025 | L | Columbus Clingstones 10 at Biloxi Shuckers 3 | Final |
| August 16, 2025 | W | Columbus Clingstones 3 at Biloxi Shuckers 13 | Final |
| August 17, 2025 | L | Columbus Clingstones 7 at Biloxi Shuckers 3 | Final |
| August 19, 2025 | L | Chattanooga Lookouts 7 at Biloxi Shuckers 3 | Final |
| August 20, 2025 | L | Chattanooga Lookouts 6 at Biloxi Shuckers 3 | Final |
| August 21, 2025 | | Chattanooga Lookouts at Biloxi Shuckers | Ppd. |
| August 22, 2025 | W | Chattanooga Lookouts 4 at Biloxi Shuckers 7 (Game 1) | Final (7) |
| August 22, 2025 | W | Chattanooga Lookouts 2 at Biloxi Shuckers 3 (Game 2) | Final (7) |
| August 23, 2025 | W | Chattanooga Lookouts 1 at Biloxi Shuckers 11 | Final |
| August 24, 2025 | W | Chattanooga Lookouts 3 at Biloxi Shuckers 9 | Final |
| August 26, 2025 | L | Biloxi Shuckers 1 at Montgomery Biscuits 2 | Final |
| August 27, 2025 | L | Biloxi Shuckers 2 at Montgomery Biscuits 3 | Final (11) |
| August 28, 2025 | L | Biloxi Shuckers 1 at Montgomery Biscuits 3 | Final |
| August 29, 2025 | | Biloxi Shuckers at Montgomery Biscuits | Ppd. |
| August 30, 2025 | L | Biloxi Shuckers 3 at Montgomery Biscuits 5 (Game 1) | Final (8) |
| August 30, 2025 | L | Biloxi Shuckers 1 at Montgomery Biscuits 3 (Game 2) | Final (7) |
| August 31, 2025 | L | Biloxi Shuckers 5 at Montgomery Biscuits 12 | Final |
| September 1, 2025 | W | Pensacola Blue Wahoos 3 at Biloxi Shuckers 6 | Final |
| September 3, 2025 | W | Pensacola Blue Wahoos 2 at Biloxi Shuckers 5 | Final |
| September 4, 2025 | L | Pensacola Blue Wahoos 2 at Biloxi Shuckers 0 | Final |
| September 5, 2025 | L | Pensacola Blue Wahoos 5 at Biloxi Shuckers 0 | Final |
| September 6, 2025 | W | Pensacola Blue Wahoos 3 at Biloxi Shuckers 5 | Final |
| September 7, 2025 | W | Pensacola Blue Wahoos 1 at Biloxi Shuckers 4 | Final |
| September 9, 2025 | W | Biloxi Shuckers 9 at Birmingham Barons 4 | Final |
| September 10, 2025 | W | Biloxi Shuckers 8 at Birmingham Barons 7 | Final (10) |
| September 11, 2025 | L | Biloxi Shuckers 6 at Birmingham Barons 7 | Final |
| September 12, 2025 | L | Biloxi Shuckers 1 at Birmingham Barons 2 | Final |
| September 13, 2025 | | Biloxi Shuckers at Birmingham Barons | 7:30 p.m. |
| September 14, 2025 | | Biloxi Shuckers at Birmingham Barons | 2:00 p.m. |
Biloxi Shuckers Schedule
