| | | |
| November 2, 2012 | L | Chicago Soul FC 13 at Syracuse Silver Knights 8 | Final |
| November 3, 2012 | W | Rochester Lancers 10 at Syracuse Silver Knights 16 | Final |
| November 10, 2012 | L | Syracuse Silver Knights 4 at Baltimore Blast 10 | Final |
| November 16, 2012 | L | Syracuse Silver Knights 8 at Missouri Comets 11 | Final |
| November 18, 2012 | L | Syracuse Silver Knights 6 at Wichita Wings 8 | Final |
| November 24, 2012 | L | Chicago Soul FC 14 at Syracuse Silver Knights 11 | Final |
| November 30, 2012 | W | Missouri Comets 7 at Syracuse Silver Knights 13 | Final |
| December 2, 2012 | W | Rochester Lancers 8 at Syracuse Silver Knights 23 | Final |
| December 8, 2012 | L | Wichita Wings 12 at Syracuse Silver Knights 10 | Final |
| December 14, 2012 | W | Missouri Comets 8 at Syracuse Silver Knights 18 | Final |
| December 22, 2012 | W | Syracuse Silver Knights 16 at Rochester Lancers 14 | Final |
| December 26, 2012 | L | Milwaukee Wave 12 at Syracuse Silver Knights 11 | Final |
| December 28, 2012 | L | Syracuse Silver Knights 8 at Wichita Wings 14 | Final |
| December 29, 2012 | L | Syracuse Silver Knights 9 at Missouri Comets 17 | Final |
| January 4, 2013 | L | Syracuse Silver Knights 0 at Chicago Soul FC 11 | Final |
| January 5, 2013 | L | Syracuse Silver Knights 10 at Milwaukee Wave 13 | Final |
| January 12, 2013 | W | Syracuse Silver Knights 15 at Rochester Lancers 14 | Final |
| January 18, 2013 | L | Baltimore Blast 14 at Syracuse Silver Knights 12 | Final |
| January 20, 2013 | L | Baltimore Blast 27 at Syracuse Silver Knights 13 | Final |
| February 1, 2013 | L | Baltimore Blast 10 at Syracuse Silver Knights 8 | Final |
| February 2, 2013 | L | Syracuse Silver Knights 6 at Baltimore Blast 11 | Final |
| February 16, 2013 | W | Syracuse Silver Knights 17 at Rochester Lancers 15 | Final (OT) |
| February 22, 2013 | W | Wichita Wings 10 at Syracuse Silver Knights 15 | Final |
| February 27, 2013 | L | Milwaukee Wave 12 at Syracuse Silver Knights 8 | Final |
| March 1, 2013 | L | Syracuse Silver Knights 6 at Chicago Soul FC 17 | Final |
| March 2, 2013 | L | Syracuse Silver Knights 6 at Milwaukee Wave 10 | Final |
