| | | |
| February 24, 2024 | L | Seattle Sounders FC 1 at Los Angeles FC 2 | Final |
| March 2, 2024 | T | Austin FC 0 at Seattle Sounders FC 0 | Final |
| March 9, 2024 | | Seattle Sounders FC at Philadelphia Union | Ppd. |
| March 16, 2024 | T | Colorado Rapids 1 at Seattle Sounders FC 1 | Final |
| March 23, 2024 | L | Seattle Sounders FC 2 at San Jose Earthquakes 3 | Final |
| March 30, 2024 | L | Seattle Sounders FC 0 at LA Galaxy 1 | Final |
| April 6, 2024 | W | Club de Foot Montreal 0 at Seattle Sounders FC 5 | Final |
| April 13, 2024 | T | Seattle Sounders FC 0 at FC Dallas 0 | Final |
| April 20, 2024 | L | Vancouver Whitecaps FC 2 at Seattle Sounders FC 0 | Final |
| April 27, 2024 | | Seattle Sounders FC at D.C. United | 7:30 p.m. |
| April 30, 2024 | | Seattle Sounders FC at Philadelphia Union | 7:30 p.m. |
| May 5, 2024 | | LA Galaxy at Seattle Sounders FC | 6:30 p.m. |
| May 12, 2024 | | Seattle Sounders FC at Portland Timbers | 4:30 p.m. |
| May 15, 2024 | | Seattle Sounders FC at Real Salt Lake | 9:30 p.m. |
| May 18, 2024 | | Vancouver Whitecaps FC at Seattle Sounders FC | 10:30 p.m. |
| May 25, 2024 | | Seattle Sounders FC at St. Louis City SC | 8:30 p.m. |
| May 29, 2024 | | Real Salt Lake at Seattle Sounders FC | 10:30 p.m. |
| June 1, 2024 | | Seattle Sounders FC at Columbus Crew SC | 7:30 p.m. |
| June 8, 2024 | | Seattle Sounders FC at Sporting Kansas City | 8:30 p.m. |
| June 15, 2024 | | Minnesota United FC at Seattle Sounders FC | 10:30 p.m. |
| June 19, 2024 | | Seattle Sounders FC at Houston Dynamo FC | 8:30 p.m. |
| June 22, 2024 | | FC Dallas at Seattle Sounders FC | 10:30 p.m. |
| June 29, 2024 | | Chicago Fire FC at Seattle Sounders FC | 10:30 p.m. |
| July 6, 2024 | | New England Revolution at Seattle Sounders FC | 10:30 p.m. |
| July 13, 2024 | | Seattle Sounders FC at Austin FC | 8:30 p.m. |
| July 17, 2024 | | St. Louis City SC at Seattle Sounders FC | 10:30 p.m. |
| July 20, 2024 | | Los Angeles FC at Seattle Sounders FC | 10:30 p.m. |
| August 24, 2024 | | Seattle Sounders FC at Minnesota United FC | 10:30 p.m. |
| August 31, 2024 | | Seattle Sounders FC at Portland Timbers | 10:30 p.m. |
| September 15, 2024 | | Sporting Kansas City at Seattle Sounders FC | 7:00 p.m. |
| September 18, 2024 | | San Jose Earthquakes at Seattle Sounders FC | 10:30 p.m. |
| September 28, 2024 | | Houston Dynamo FC at Seattle Sounders FC | 10:30 p.m. |
| October 2, 2024 | | Seattle Sounders FC at Vancouver Whitecaps FC | 10:30 p.m. |
| October 5, 2024 | | Seattle Sounders FC at Colorado Rapids | 9:30 p.m. |
| October 19, 2024 | | Portland Timbers at Seattle Sounders FC | 9:00 p.m. |
Seattle Sounders FC Schedule
